What separates the super-villains from just plain old villains? When they escape from prison, regular villains might lay low for a while and enjoy the sweet taste of freedom. But not a super-villain like Doctor Octopus--the minute he's free, he's gathering up the most dangerous crew ever assembled: the Vulture, Electro, Kraven the Hunter, Sandman and Mysterio! And they've all got one thing on their minds: bringing down Spider-Man once and for all! As if that weren't enough for this two-part epic, maybe we should mention that Spidey's powers are on the fritz, and he's only got the abilities of...a regular teenager?!